Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.

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2,866 – 2,880 of 9,509 results

2,866

Ambeed AMBEED

5000892144 4-PYRIMIDIN-2-YLMORPHOLI 100MG

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2,867

Ambeed AMBEED

5000895041 1-PYRIMIDIN-4-YLETHANONE 250MG

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2,868

Medchemexpress LLC Benzoic acid, 4-[5-[(2-furanylmethyl)amino]-1,2,4-triazolo[4,3-c]pyrimidin-8-yl]- | 2467965-71-3 | MFCD32701933 | 99.9% | C17H13N5O3 | 10MG

EED226-COOH is an EED-targeting ligand derived from EED226 designed for PROTAC development. It binds the EED subunit of PRC2 and is intended for conjugation to E3 ligase ligands to generate targeted protein degraders. The compound is supplied as an off-white to light-yellow solid and is provided with analytical characterization for biochemical and cell-based research.

Purity 99.9% (analytical).
Molecular formula C17H13N5O3.
Molecular weight 335.32 g·mol-1.
Solubility in DMSO 125 mg/mL (requires ultrasonic treatment).
Storage powder: -20°C (long-term) or 4°C (shorter term).
Includes datasheet, 1H NMR, LC-MS, COA, and SDS documentation.

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2,869

eMolecules 1123231-07-1 | (1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine | MFCD20527803 | 50mg

Medchem Express | ADRA1D receptor antagonist 1 | 5mg | 778475771 | HY-135270 | 1191908-14-1 | 337.200 | C15H14Cl2N4O

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2,870

eMolecules 2649372-20-1 | Medchem Express | B-Raf IN 2 | 5mg | 713704836 | HY-145120 | 461.44 | C20H17F2N5O4S

Medchem Express | Alternariol | 1mg | 536984959 | HY-N6714 | 641-38-3 | MFCD00133068 | 258.229 | C14H10O5

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2,871

Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG

This product is an orally active dual inhibitor for two specific kinases, with very low nanomolar inhibitory concentrations. It is designed for use in cancer research, particularly in the field of tumor immunity.

Potent dual inhibition against targeted kinases (IC50: 1 nM, 5.6 nM).
Enhances immune response to anti-PD-L1 treatments, inducing immune memory in animal models.
Demonstrates antitumor activity and prolongs survival in animal models with anti-PD-L1 combination.
Induces immunologic memory in tumor cells when combined with anti-PD-L1.
Promotes IL-2 and IFN-γ secretion in T cells and IL-2 in Jurkat cells.
Blocks immunosuppressive cytokine production by spheroid cell lines without cytotoxicity.
Orally active for convenient administration.

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2,872

eMolecules 1381930-17-1 | Medchem Express | TBK1/IKK-IN-4 | 5mg | 673358836 | HY-124652 | 533.633 | C28H35N7O4

Medchem Express | C-021 (dihydrochloride) | 1mg | 495799537 | HY-103364A | 1784252-84-1 | MFCD16618393 | 540.570 | C27H43Cl2N5O2

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2,873

eMolecules 2467965-71-3 | EED226-COOH | AstaTech335.323 | C17H13N5O3 | 95.000 | OC(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12 | 0.1g | 562552109

EED226-COOH | AstaTech | 2467965-71-3335.323 | C17H13N5O3 | 95.000 | OC(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12 | 0.1g | 562552109

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2,874

eMolecules 54376-50-0 | 5-fluoro-2-methyl-pyrimidine | Pharmablock | MFCD16611294 | 112.107 | C5H5FN2 | 97.000 | Cc1ncc(F)cn1 | 25mg | 788564172

5-fluoro-2-methyl-pyrimidine | Pharmablock | 54376-50-0 | MFCD16611294 | 112.107 | C5H5FN2 | 97.000 | Cc1ncc(F)cn1 | 25mg | 788564172

Pricing & Availability

2,875

eMolecules 94222-07-8 | 1-(2-Chloro-4-pyrimidinyl)-4-piperidinol | Synthonix | MFCD09743694 | 213.670 | C9H12ClN3O | 95.000 | OC1CCN(CC1)c1ccnc(Cl)n1 | 500mg | 786490886

1-(2-Chloro-4-pyrimidinyl)-4-piperidinol | Synthonix | 94222-07-8 | MFCD09743694 | 213.670 | C9H12ClN3O | 95.000 | OC1CCN(CC1)c1ccnc(Cl)n1 | 500mg | 786490886

Pricing & Availability

2,876

eMolecules 2757804-89-8 | Medchem Express | PI3K | Akt | mTOR-IN-2 | 5mg | 742367738 | HY-146751 | 285.294 | C17H13F2NO

Ambeed | 10-Ethyl-378-trimethylbenzo[g]pteridine-24(3H10H)-dione | 50mg | 666597797 | A1219873 | 67767-38-8 | 284.319 | C15H16N4O2

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2,877

Medchemexpress LLC Methyl-4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-1-yl) | 1062169-56-5 | 98.0% | 5 MG

WYE-354 is an ATP-competitive mTOR inhibitor used in research to block mTORC1 and mTORC2 signaling and to study PI3K/mTOR pathway modulation in vitro. It is supplied as a high-purity small molecule in solid form or as a ready-to-use DMSO solution for laboratory assays.

ATP-competitive mTOR inhibitor with IC50 ≈ 5 nM.
High purity suitable for biochemical and cell-based assays.
Available as solid and as a 10 mM solution in DMSO for convenience.
Molecular weight 495.53 g·mol⁻¹ and formula C24H29N7O5.
Commonly used for pathway, signaling, and autophagy research in vitro.

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2,878

Medchemexpress LLC HY-114414 5mg Medchemexpress, HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 Purity:>98%

Medchemexpress, HY-114414 5mg HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC 50 s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,879

eMolecules 1609960-30-6 | Medchem Express | TH287 | 5mg | 446267994 | HY-16965 | MFCD29035111 | 269.13 | C11H10Cl2N4

Medchem Express | E7766 (diammonium salt) | 1mg | 694124877 | HY-111999A | 2242635-03-4 | 780.660 | C24H32F2N12O8P2S2

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2,880

eMolecules 271-70-5 | 7H-pyrrolo[2,3-d]pyrimidine | Pharmablock | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 25g | 551185312

7H-pyrrolo[2,3-d]pyrimidine | Pharmablock | 271-70-5 | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 25g | 551185312

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Pyrimidines And Derivatives

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Medchemexpress LLC Benzoic acid, 4-[5-[(2-furanylmethyl)amino]-1,2,4-triazolo[4,3-c]pyrimidin-8-yl]- | 2467965-71-3 | MFCD32701933 | 99.9% | C17H13N5O3 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Methyl-4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-1-yl) | 1062169-56-5 | 98.0% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-114414 5mg Medchemexpress, HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Benzoic acid, 4-[5-[(2-furanylmethyl)amino]-1,2,4-triazolo[4,3-c]pyrimidin-8-yl]- | 2467965-71-3 | MFCD32701933 | 99.9% | C17H13N5O3 | 10MG

Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG

Medchemexpress LLC Methyl-4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-1-yl) | 1062169-56-5 | 98.0% | 5 MG

Medchemexpress LLC HY-114414 5mg Medchemexpress, HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 Purity:>98%